![]() One such study simulated insomnia by keeping participants awake with loud traffic noise. Using mirtazapine as a sleep aid has been looked at in a handful of studies in healthy volunteers and it’s been shown to improve sleep. Some may notice sleep improvement from the first dose and for others the effect may be more gradual. When low dose mirtazapine is taken for sleep problems it may start to have an effect anywhere from 1-2 weeks after initially taking it. When the drug is taken for depression or anxiety, NHS guidelines note that it may take between 4-6 weeks for beneficial effects to become apparent. It can take a few weeks for the effects of mirtazapine to become noticeable. Some people may find that mirtazapine at 3.75mg may be their ideal dose. Generally, it’s given at a starting dose of 7.5mg mirtazapine, to be taken at bedtime. It’s worth noting that the sedative effects of mirtazapine are thought to be greater at low dose and are lost at higher dose. If you are prescribed mirtazapine for sleep problems, it’s usually given at a low dosage. If found necessary, 45mg mirtazapine can be given as a single dose per day or split into two doses during the day. After this time, the dose may be adjusted to suit how your body is responding to it. When mirtazapine is prescribed to treat depression or anxiety, it’s initially recommended at a dose of 15–30 mg per day, taken at bedtime, for two to four weeks. It’s also available in a liquid form, at a dose of 15mg per ml. Mirtazapine is available as 15mg, 30mg and 45mg doses, in both standard tablet form and dispersible tablet form. Weight gain is also considered a common side-effect of mirtazapine, with one study on healthy males concluding that the drug may change the user’s metabolism slightly and increase cravings for sweet foods. It may also increase the occurrence of restless legs syndrome and periodic limb movements 4 both of which can significantly disrupt your sleep. It can also leave some people feeling groggy or feeling like they have a slight hangover, so following the prescribed dosage is very important. While mirtazapine may help you to sleep better while you’re taking it, it’s well recognised that insomnia can develop after stopping taking the drug.ĭue to its sedating effects, mirtazapine can lead to daytime drowsiness. It’s interesting to note that mirtazapine may cause ‘sleep disorders’, with fatigue also being a common side effect.
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